Analyze and model the living
Semester 1 (September-January)
Objectives (in terms of know-how) :
- To know how to estimate the orders of magnitude of cell biology.
- To know how to use the basics of chemical kinetics in the context of a cell biology problem.
- Know how to use a numerical calculation tool to solve a problem of modeling biological systems.
Brief program :
* Part 1 : Cell biology by the number (8 hours of lectures and 4 hours of practical work)Size & Geometry ; Concentrations & Absolute Numbers ; Energis & Forces ; Rates & Durations
* Part 2 : Mathematical Modelling in Systems Biology (24 hours of lectures and 12 hours of practical work)
Modelling Chemical Reaction Networks ; Biochemical Kinetics ; Analysis of Dynamic Mathematical Models
Semester 2 (January-June)
Objectives (in terms of know-how) :
- Know how to build a mathematical model from information in the literature.
- Know how to use a numerical calculation tool to estimate the possible values of parameters from experimental results,
Brief program :
* Part 1 : Mathematical Modelling in Systems Biology :
Metabolic Networks, Signal Transduction Pathways, Gene Regulatory Networks
* Part 2 : Data Driven Models :
Data for Small Metabolic and Signaling Systems, Parameter Estimation, Reduction and Coupling of Models, Model Selection
- Teacher: Francois Anquez
- Teacher: Benjamin Pfeuty
- Teacher: Quentin Thommen